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Year : 2017  |  Volume : 55  |  Issue : 4  |  Page : 278-281

Optical coherence tomography-based assessment of central macular thickness after penetrating keratoplasty

1 Department of Ophthalmology – Patna Medical College and Hospital, Patna, Bihar, India
2 Department of Ophthalmology - RIO/ IGIMS, Patna, Bihar, India

Correspondence Address:
Dr. Mamta Singh
Patna Medical College and Hospital, Patna - 800 004, Bihar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjosr.tjosr_3_18

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Purpose: To assess the pattern of change in central macular thickness (CMT) after penetrating keratoplasty (PKP) with the help of optical coherence tomography (OCT) and to know the prevalence and prognosis of cystoid macular edema (CME) in these patients. Materials and Methods: A hospital-based prospective study of 13 eyes of 13 patients of PKP was conducted. Eleven of them underwent PKP and two of them underwent triple procedure. Postoperative CMT analysis was done with OCT at the end of 1st, 2nd, and 3rd month. CME has been defined as CMT >250 μ, loss of normal foveal contour, and cystoid changes in the central macula. Patients with macular edema were continued with the routine postoperative regimen of PKP. Results: The CMT at the end of 1, 2, and 3 months were 253.46 ± 37.50 μ, 230 ± 34.89 μ, and 214.53 ± 33.84 μ, respectively. The statistical difference between 1st and 2nd month and between 2nd and 3rd month was very significant. The prevalence of CME at the end of 1st, 2nd, and 3rd month was 30.7%, 23.07%, and 7.69% respectively. At month 1, 42.85% cases of pseudophakic bullous keratopathy and 16.66% cases of corneal opacity patients had CME. Triple procedure is associated with higher CMT in comparison to simple keratoplasty, but this difference was not significant statistically. Conclusion: There is a gradual decline in CMT and prevalence of macular edema with time. Hence, not every case of diagnosed macular edema after PKP needs to be treated very aggressively. Triple procedure without vitreous manipulations has no separate implication on incidence of CME, than a routine PKP.

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