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Year : 2017  |  Volume : 55  |  Issue : 4  |  Page : 318-320

Invasive ocular surface squamous neoplasia in congenital ichthyosiform erythroderma

Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Dhivya Ashok Kumar
Dr. Agarwal's Eye Hospital and Eye Research Centre, 19, Cathedral Road, Chennai - 600 086, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjosr.tjosr_18_18

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We report an invasive type of ocular surface squamous neoplasia (OSSN) in a patient with congenital ichthyosiform erythroderma. A male patient aged 44 years, with ichthyosis presented with progressively growing right corneal mass, with decreasing vision. He was clinically diagnosed as OSSN and treated with local excision, conjunctival cryotherapy, and ocular surface reconstruction with amniotic membrane graft. Histopathological examination of the excised specimen confirmed the mass as a well-differentiated squamous cell carcinoma with invasion into the corneal stroma. Postoperatively, ocular surface reconstruction was achieved, and visual acuity improved from only perception of light to counting fingers one meter due to dense corneal scar. Postoperative central corneal scar with thinning was noted. Early age of onset and progression of OSSN in such patient with ichthyosis, recommend the need for screening in patients with congenital ichthyosis. Early treatment can prevent visual disability and permanent sequelae due to corneal scar.

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