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Year : 2019  |  Volume : 57  |  Issue : 2  |  Page : 109-112

Topical nepafenac in the treatment of center involving diabetic macular edema

Department of Retina-Vitreous, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, India

Correspondence Address:
Dr. T P Vignesh
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, No. 1, Anna Nagar, Madurai - 625 020, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjosr.tjosr_12_19

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Purpose: To assess the efficacy of topical nepafenac 0.1% in the treatment of center-involving diabetic macular edema (DME). Design: A prospective, interventional case series. Methods: Fourteen eyes of thirteen patients with center-involving DME were included in the study, and they were administered topical nepafenac eye drops 0.1% thrice daily, for 6 months. Vision and foveal thickness were recorded at the baseline and 2nd, 4th, and 6th month follow-up visits. Results: The mean baseline and final LogMAR visual acuity were 0.35 and 0.18, respectively, and the mean baseline and final foveal thickness were 463.4 μm and 291.8 μm, respectively, both showing a statistically significant improvement (P < 0.05). Conclusion: Topical nepafenac is effective in the treatment of center-involving DME in this small case series; however, a large randomized study is warranted.

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