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 Table of Contents  
OPHTHALMIC IMAGES
Year : 2021  |  Volume : 59  |  Issue : 4  |  Page : 415

Ectopia lentis in marfan syndrome


Department of Glaucoma Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India

Date of Submission02-Mar-2020
Date of Decision10-Apr-2020
Date of Acceptance21-Apr-2020
Date of Web Publication21-Dec-2021

Correspondence Address:
Dr. Vijayalakshmi A Senthilkumar
Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tjosr.tjosr_13_20

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How to cite this article:
Senthilkumar VA, Vineela P. Ectopia lentis in marfan syndrome. TNOA J Ophthalmic Sci Res 2021;59:415

How to cite this URL:
Senthilkumar VA, Vineela P. Ectopia lentis in marfan syndrome. TNOA J Ophthalmic Sci Res [serial online] 2021 [cited 2022 Oct 7];59:415. Available from: https://www.tnoajosr.com/text.asp?2021/59/4/415/333156



A 17-year-old male presented to us with decreased vision in both eyes (BE) since childhood. His best-corrected visual acuity was 6/24 in the right eye and 6/12 in the left eye. Slit lamp examination after dilatation revealed subluxated crystalline lens temporally with visible edges of the lens in BE [Figure 1]a and [Figure 1]b. Systemic examination of the patient showed marfanoid features as tall stature (175 cm), thin spider-like fingers with mitral regurgitation. The patient underwent sequential pars plana lensectomy and scleral fixated intraocular lens in BE. Marfan syndrome is an autosomal dominant disease, characterized by ocular, musculoskeletal, and cardiac manifestations. It is caused by mutations in FBN1 gene, which codes for fibrillin protein.[1] Ectopia lentis or lens subluxation is seen in 60%–80% of Marfan syndrome patients. Lens subluxation is usually bilateral and superotemporal or temporal. It can vary from asymptomatic condition to significant subluxation, in which the equator of the lens is in the pupillary axis causing diplopia or decreased vision.[2],[3]
Figure 1: (a) Slit lamp photograph of the right eye after dilatation with diffuse illumination showing temporally subluxated crystalline lens with the visibility of the edge of the lens in the pupillary axis. (b) Slit lamp photograph of the right eye after dilatation with retroillumination showing the decreased number of ciliary zonules, as well as increased space between the zonules

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Stanković-Babić G, Vujanović M, Đorđević-Jocić J, Cekić S. Ocular features of Marfan syndrome. Med Biol 2008;15:37-40.  Back to cited text no. 1
    
2.
Nahum Y, Spierer A. Ocular features of Marfan's syndrome: Diagnosis and management. Isr Med Assoc J 2008;10:179-81.  Back to cited text no. 2
    
3.
Anteby I, Isaac M, BenEzra D. Hereditary subluxated lenses: Visual performances and long-term follow-up after surgery. Ophthalmology 2003;110:1344-8.  Back to cited text no. 3
    


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